Hardware
The cellZscope measures the impedance of barrier-forming cell cultures
grown on permeable membranes. It works with standard cell culture
inserts and is fully compatible with a broad range of inserts from
different manufacturers, e.g. BD Biosciences, Corning, Greiner Bio-One,
Millipore, and Nunc. The cell module can be loaded with a maximum of
24 inserts simultaneously. Three versions of the module are available
which are optimized for use with small ("24-well" type), mid-sized ("12-well" type), or
large ("6-well" type) inserts, respectively. During an experiment the
cell module is typically placed inside a standard incubator while the
external controller is connected to a computer running the cellZscope
software.
| The design of the cell module warrants easy handling also under an airflow work bench. The two top covers can separately be lifted to gain free access to the wells for loading with standard cell culture inserts. |  |
| The inner and outer compartments can be reached with a pipette for convenient media exchange, cell seeding and / or adding of substances. Both the apical and the basolateral side of the cells remain fully accessible throughout the experiments. |  |
| The hinged lids can be opened without having to remove the electrodes from the wells while an experiment is running. |  |
| Openings in the transparent cover give access to the inner and outer compartment of each well. Medium can easily be exchanged and substances added with a pipette. |  |
Corning is a registered trademark of Corning Inc. Millipore is a registered trademark of Millipore Corp. Greiner is a registered trademark of Greiner Bio-One GmbH. BD is a trademark of Becton, Dickinson and Company. Nunc is a trademark of Thermo Fisher Scientific Inc. All other brand or product names are trademarks or registered trademarks of their respective holders.